KEYNOTE-006-Studie: 4-Jahres-Überleben und Ergebnisse nach Absetzen von Pembrolizumab (Pembro) nach zwei Jahren bei Patienten mit Ipilimumab-naivem fortgeschrittenen Melanom
ASCO Annual Meeting 2018 – Abstract: No. 9503, Long, GV et al.: KEYNOTE-006-Studie
4-year survival and outcomes after cessation of pembrolizumab (pembro) after 2-years in patients (pts) with ipilimumab (ipi)-naive advanced melanoma in KEYNOTE-006.
Conclusion:
“Pembro provides durable antitumor activity in treatment-naive or -experienced pts with advanced melanoma. Of pts who completed 2 y pembro, 86% were progression free at 20 mo. Pembro is safe and provides additional antitumor activity as second-course treatment.”
Clinical trial information: NCT01866319
Quelle:
Long, GV et al. ASCO 2018, Oral Abstract Session
J Clin Oncol 36, 2018 (suppl; abstr 9503)